Carbonyl compounds
Complex Ketones
(4,313)
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Dicarbonyl Compounds
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Alpha beta-unsaturated carbonyl compounds
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Medchemexpress LLC CHMFL-PI4K-127 | 2377604-81-2 | C18H15ClN4O3S | 5 MG
CHMFL-PI4K-127 (compound 15g) is an orally active, potent, and highly selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor, with an IC50 of 0.9 nM. It exhibits potent activity against 3D7 Plasmodium falciparum, with an EC50 of 25.1 nM, and shows antimalaria efficacy. This product is for research use only and not for sale to patients.
- Potent and highly selective PfPI4K inhibitor
- Orally active
- Exhibits potent activity against 3D7 Plasmodium falciparum
- Shows antimalaria efficacy
- Demonstrates high selectivity against PfPI4K over human lipid and protein kinases
- Effective against drug-resistant strains of P. falciparum
- Significant in vivo antimalarial activities in rodent models
- Provides full protection and cure at 1 mg/kg in liver stage infection
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Medchemexpress LLC Crocetin dialdehyde | 502-70-5 | 296.40 | 5 MG
Crocetin dialdehyde is a non-volatile apocarotenoid. It is derived from the action of the plastidic enzyme CCD2 on the carotenoid zeaxanthin, found in saffron. Crocetin dialdehyde can be converted into Crocetin (HY-N2072) by aldehyde dehydrogenases (ALDHs). Studies in mice have shown that Crocetin dialdehyde has no effect on the liver.
- Non-volatile apocarotenoid.
- Can be converted to Crocetin by ALDHs.
- No observed effect on the liver in mice (at 300 mg/kg, p.o., for 1 week).
- Purity: 99.21%.
- Appearance: Solid, orange to reddish brown.
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Medchemexpress LLC Niclosamide-13C6 | 1325808-64-7 | MFCD20036278 | 99.0% | 1 MG
Niclosamide-13C6 | 1325808-64-7 | MFCD20036278 | 99.0% | 1 MG